The embryo is a person, a unique individual with its own DNA, that would, if allowed, grow into a fully functioning human being
The end doesn't justify the means
There are alternatives to the use of embryos, and most doctors now see more promise in getting stem cells through other means
Experiments on animals have had very mixed results, and required hundreds of attempts
There have always been strict legal limits to the use of embryos in research, showing that the government want to limit what researchers can do with embryos
There are serious risks to patients - the effects of treatments are unknown and could be very damaging
It's a slippery slope - once you allow researchers to experiment up to 14 days, they will then want to go further and push the boundaries. If you allow research at 14 days, why not 15 days or 30 days?
Companies have already patented human genes - we are now treating embryos as a commodity, something that has no intrinsic worth (value in itself), only instrumental worth (value in its usefulness)